Prinicipal investigator University of Kentucky Lexington, Kentucky
RNA interference is quickly becoming established as an alternative to existing, broad-spectrum insecticides. What isn't fully understood, is how environmental factors influence the efficacy of RNAi in the field. Here the Colorado Potato Beetle is used to assess RNAi efficacy, under varying thermal and dietary regimes. Using a novel experimental design that quantifies consumption of potato, we show that changes in climate can significantly affect the efficacy of RNAi.